Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066309 | 0.84 | RAB9A (0.47) | MEN1GAAKMT2A | |
| SCHEMBL28626965 | 0.81 | AAK1 (0.46) | AAK1HDAC1MEN1GAAKMT2A | |
| SCHEMBL7065211 | 0.78 | IDO1 (0.39) | PPARGPPARAHDAC1MEN1GAA | |
| SCHEMBL7068935 | 0.77 | AAK1 (0.41) | AAK1PPARGPPARAHDAC1ERAP2 | |
| SCHEMBL6492339 | 0.77 | BRD4 (0.46) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL5563988 | 0.76 | CYP1A2 (0.45) | AAK1HDAC1MEN1GAAKMT2A | |
| SCHEMBL29765467 | 0.75 | AAK1 (0.46) | AAK1HDAC1MEN1GAAKMT2A | |
| SCHEMBL246277 | 0.75 | AAK1 (0.46) | AAK1HDAC1MEN1GAAKMT2A | |
| SCHEMBL14876842 | 0.72 | GAA (0.54) | AAK1MEN1GAAKMT2AALOX15 | |
| SCHEMBL5563026 | 0.72 | KCNQ3 (0.45) | AAK1HDAC1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |