SCHEMBL706933

SCHEMBL706933

CS(=O)(=O)C12CC3CC(C1)C(N)C(C3)C2

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 10/20 0.38
HSD11B2 P80365 6/20 0.38
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1046456 0.82 HSD11B1 (0.42) HSD11B1HSD11B2
SCHEMBL9001234 0.80 GAA (0.39) HSD11B1HSD11B2MAPT
SCHEMBL3108060 0.73 HSD11B1 (0.53) HSD11B1HSD11B2
SCHEMBL20456978 0.73 HSD11B1 (0.42) HSD11B1HSD11B2
SCHEMBL19248215 0.73 HSD11B1 (0.42) HSD11B1HSD11B2
SCHEMBL13195555 0.72 LMNA (0.36) HSD11B1
SCHEMBL1406851 0.72 LMNA (0.36) HSD11B1
SCHEMBL1160739 0.72 LMNA (0.36) HSD11B1
SCHEMBL13182801 0.69
SCHEMBL1222916 0.69 HSD11B1 (0.34) HSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111050583-B Adhesive viscoelastic body and use thereof in stable storage container 塔克罗吉科有限责任公司 2022-05-27 CN disclosed
US-11046482-B1 Adhesive viscoelastic polymer and its use in lighting apparatus Tak Logic, LLC (US) 2021-06-29 US disclosed
CN-107428892-B Photocurable composition for three-dimensional printing 陶氏环球技术有限责任公司 2021-05-04 CN disclosed
CN-111050583-A Adhesive viscoelastic body and use thereof in stable storage container 塔克罗吉科有限责任公司 2020-04-21 CN disclosed
CN-106715505-B Epoxy compositions containing acrylate-based tougheners 陶氏环球技术有限责任公司 2020-03-27 CN disclosed
US-10450401-B2 Polyurethane foam with aqueous polymer dispersion DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-22 US disclosed
US-20180046076-A1 Photocurable Compositions for Three-Dimensional Printing DOW GLOBAL TECHNOLOGIES LLC (US) 2018-02-15 US disclosed
US-20170320995-A1 Polyurethane Foam with Aqueous Polymer Dispersion DOW GLOBAL TECHNOLOGIES LLC 2017-11-09 US disclosed
US-20170218111-A1 EPOXY COMPOSITION CONTAINING ACRYLATE BASED TOUGHENING AGENT DOW GLOBAL TECHNOLOGIES LLC 2017-08-03 US disclosed
US-8735460-B2 Foamed isocyanate-based polymer, a mix and process for production thereof DuPont Nutrition BioScience ApS (DK) 2014-05-27 US disclosed
US-7465757-B2 Foamed isocyanate-based polymer, a mix and process for production thereof DANISCO A/S (DK) 2008-12-16 US disclosed
US-20080249202-A1 Method for the Production of Polyisocyanates HUNTSMAN INTERNATIONL LLC (US) 2008-10-09 US disclosed
CN-101268113-A Method for the production of polyisocyanates HUNTSMAN INT LLC (US) 2008-09-17 CN disclosed
US-20060241199-A1 Foamed isocyanate-based polymer, a mix and process for production thereof DANISCO A/S (DK) 2006-10-26 US disclosed
US-20060122355-A1 Derivatized highly branched polysaccharide and a mix for production of polyurethane thereof DANISCO A/S (DK) 2006-06-08 US disclosed
US-20060122286-A1 Foamed isocyanate-based polymer, a mix and process for production thereof DANISCO A/S (DK) 2006-06-08 US disclosed
US-20060111459-A9 Flame retardant composition and polyurethane foam containing same BRADFORD LARRY L 2006-05-25 US disclosed
US-20050240000-A1 Dendritic macromolecule with improved polyether polyol solubility and process for production thereof PERSTORP AB (SE) 2005-10-27 US disclosed
US-20050159498-A1 Flame retardant composition and polyurethane foam containing same SUPRESTA LLC 2005-07-21 US disclosed
US-20030176591-A1 Dendritic macromolecule with improved polyether polyol solubility and process for production thereof PERSTORP AB (SE) 2003-09-18 US disclosed