Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.48 |
| ▸ | CTSK | P43235 | 9/20 | 0.48 |
| ▸ | CTSL | P07711 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761305 | 0.87 | CTSS (0.51) | CTSSCTSKCTSL | |
| SCHEMBL5761200 | 0.78 | CTSS (0.53) | CTSSCTSKCTSL | |
| SCHEMBL4456156 | 0.75 | CTSS (0.59) | CTSSCTSKCTSL | |
| SCHEMBL4456154 | 0.75 | CTSS (0.59) | CTSSCTSKCTSL | |
| SCHEMBL5761069 | 0.73 | CTSS (0.60) | CTSSCTSKCTSL | |
| SCHEMBL5758689 | 0.71 | CTSS (0.58) | CTSSCTSKCTSL | |
| SCHEMBL5758653 | 0.67 | CTSS (0.53) | CTSSCTSKCTSL | |
| SCHEMBL5423232 | 0.67 | CTSS (0.50) | CTSSCTSKCTSL | |
| SCHEMBL14562908 | 0.67 | CTSS (0.50) | CTSSCTSKCTSL | |
| SCHEMBL4450101 | 0.66 | CTSS (0.61) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087939-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087939-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | SDHA, LONP1, SUCNR1 | CTSS 15/4885CTSK 100/4885CTSL 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.