Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166531 | 0.86 | NCOA1 (0.50) | MAPTKDM4ELMNACYP3A4NCOA1 | |
| Benzo[D]Oxazole SCHEMBL27928999 | 0.75 | LMNA (0.66) | MAPTKDM4ELMNACYP3A4NCOA1 | |
| SCHEMBL3938313 | 0.73 | MAPT (0.58) | MAPTKDM4ELMNACYP3A4NCOA1 | |
| SCHEMBL50811 | 0.73 | TDP1 (0.48) | MAPTKDM4ELMNACYP3A4HTT | |
| SCHEMBL217044 | 0.72 | MAPT (1.00) | MAPTKDM4ELMNACYP3A4NCOA1 | |
| SCHEMBL10054248 | 0.72 | HTR2A (0.39) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| Phosphine SCHEMBL28474623 | 0.72 | TDP1 (0.46) | MAPTKDM4ELMNACYP3A4HTT | |
| Iodide SCHEMBL16916967 | 0.72 | TDP1 (0.46) | MAPTKDM4ELMNACYP3A4HTT | |
| SCHEMBL9374720 | 0.72 | CCR1 (0.61) | MAPTKDM4ELMNACYP3A4HSP90AA1 | |
| SCHEMBL1415999 | 0.71 | LMNA (0.69) | MAPTKDM4ELMNACYP3A4NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214833-A1 | Tricyclic heteroaromatic compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-10-28 | — | — | US | disclosed |
| WO-2004089950-A1 | TRICYCLIC HETEROAROMATIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214833-A1 | Tricyclic heteroaromatic compounds | CYP1A1, SULT2A1, CYP1B1 | MAPT 1759/4885KDM4E 3288/4885LMNA 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.