Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068044 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL7681882 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRAOX1TRIM24HPGD | |
| SCHEMBL7074229 | 0.80 | TTR (0.55) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL10106384 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL10106357 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL10106362 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL10106328 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL10106350 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 | |
| SCHEMBL16930085 | 0.72 | ALDH1A1 (0.59) | ALDH1A1TSHRFDPSAOX1MAPT | |
| SCHEMBL10106339 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TSHRFDPSAOX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | NITZ THEODORE J (US) | 2003-05-15 | — | — | US | disclosed |
| US-6495580-B1 | A BENZYLIDENE DERIVATIVE CONTAINING HETEROCYCLIC RING IS USEFUL AS PNEUMOVIRUS INHIBITOR | VIROPHARMA INCORPORATED | 2002-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | TTPA, HAVCR2, PML | ALDH1A1 3369/4885TSHR 4829/4885FDPS 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.