SCHEMBL7069930

SCHEMBL7069930

CCCCS(=O)(=O)O/C(=C(\C#N)c1ccc(Cl)cc1)c1ccccc1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.37
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
PGR P06401 1/20 0.32
DDR1 Q08345 1/20 0.32
SLC22A12 Q96S37 2/20 0.31
MAPT P10636 2/20 0.31
P2RX7 Q99572 1/20 0.31
LTC4S Q16873 1/20 0.31
HSD11B1 P28845 1/20 0.31
MEN1 O00255 1/20 0.31
CNR1 P21554 1/20 0.31
GPR183 P32249 1/20 0.31
CNR2 P34972 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069934 1.00 MGLL (0.37) MGLLKMT2AGAAPPARGPPARA
SCHEMBL7069829 0.90 TP53 (0.32) KMT2AGAAMEN1CNR1GPR183
SCHEMBL7069830 0.90 TP53 (0.32) KMT2AGAAMEN1CNR1GPR183
SCHEMBL7068910 0.84 ESR1 (0.32) GAAPPARGMAPT
SCHEMBL7068913 0.84 ESR1 (0.32) GAAPPARGMAPT
SCHEMBL7070125 0.83 MGLL (0.37) MGLLKMT2AGAAPPARGPPARA
SCHEMBL7070068 0.83 MGLL (0.37) MGLLKMT2AGAAPPARGPPARA
SCHEMBL7073006 0.82 MGLL (0.39) MGLLKMT2AGAAPPARGPPARA
SCHEMBL7073005 0.82 MGLL (0.39) MGLLKMT2AGAAPPARGPPARA
SCHEMBL7073489 0.82 SLC22A12 (0.35) KMT2APGRSLC22A12MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996614-B1 ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA (JP) 2003-06-11 EP disclosed
US-6187944-B1 A PHENYL ACRYLONITRILE COMPOUNDS USEFUL AS ACTIVE INGREDIENTS OF AN INSECTICIDE, A MITICIDE, A NEMATICIDE, A SOIL PESTICIDE, A FUNGICIDE AND A MARINE ANTIFOULING AGENT ISHIHARA SANGYO KAISHA LTD. (JP) 2001-02-13 US disclosed