Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069829 | 1.00 | TP53 (0.32) | TP53SMN1; SMN2ESR1LMNAGAA | |
| SCHEMBL7068910 | 0.94 | ESR1 (0.32) | SMN1; SMN2ESR1LMNAGAAF2R | |
| SCHEMBL7068913 | 0.94 | ESR1 (0.32) | SMN1; SMN2ESR1LMNAGAAF2R | |
| SCHEMBL7070762 | 0.91 | LMNA (0.34) | SMN1; SMN2ESR1LMNAGAAKMT2A | |
| SCHEMBL7070760 | 0.91 | LMNA (0.34) | SMN1; SMN2ESR1LMNAGAAKMT2A | |
| SCHEMBL7069934 | 0.90 | MGLL (0.37) | GAAMEN1CNR1GPR183CNR2 | |
| SCHEMBL7069930 | 0.90 | MGLL (0.37) | GAAMEN1CNR1GPR183CNR2 | |
| SCHEMBL7070120 | 0.76 | LMNA (0.40) | SMN1; SMN2LMNAGAA | |
| SCHEMBL7070349 | 0.76 | LMNA (0.40) | SMN1; SMN2LMNAGAA | |
| SCHEMBL7073489 | 0.74 | SLC22A12 (0.35) | TP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996614-B1 | ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2003-06-11 | — | — | EP | disclosed |
| US-6187944-B1 | A PHENYL ACRYLONITRILE COMPOUNDS USEFUL AS ACTIVE INGREDIENTS OF AN INSECTICIDE, A MITICIDE, A NEMATICIDE, A SOIL PESTICIDE, A FUNGICIDE AND A MARINE ANTIFOULING AGENT | ISHIHARA SANGYO KAISHA LTD. (JP) | 2001-02-13 | — | — | US | disclosed |