Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.49 |
| ▸ | ITGAL | P20701 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGFR | P43088 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069945 | 1.00 | TSHR (0.53) | TSHRCASP1SMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL7770050 | 0.88 | MAPT (0.44) | TSHRCASP1SMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL30480708 | 0.86 | MAPT (0.47) | TSHRCASP1SMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL615861 | 0.86 | MAPT (0.47) | TSHRCASP1SMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL615860 | 0.86 | MAPT (0.47) | TSHRCASP1SMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL1196433 | 0.82 | ABL1 (0.54) | SMN1; SMN2ITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL1196428 | 0.82 | ABL1 (0.54) | SMN1; SMN2ITGB2ICAM1ITGALPTGER3 | |
| SCHEMBL7068587 | 0.82 | ALDH1A1 (0.48) | TSHRCASP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7068592 | 0.82 | ALDH1A1 (0.48) | TSHRCASP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29406682 | 0.81 | PTGER3 (0.55) | SMN1; SMN2ITGB2ICAM1ITGALPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105367-B1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | BAYER AG (DE) | 2003-06-18 | — | — | EP | claimed |
| US-6455725-B1 | Substituted cinnamic acids and cinnamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | claimed |
| US-6455725-B1 | Substituted cinnamic acids and cinnamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |