Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068587 | 0.96 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7068592 | 0.96 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7069945 | 0.88 | TSHR (0.53) | MAPTALDH1A1KDM4ETP53PLA2G1B | |
| SCHEMBL7069948 | 0.88 | TSHR (0.53) | MAPTALDH1A1KDM4ETP53PLA2G1B | |
| SCHEMBL7071709 | 0.84 | ABL1 (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1196433 | 0.84 | ABL1 (0.54) | MAPTALDH1A1KMT2AKDM4ECYP1A2 | |
| SCHEMBL7071713 | 0.84 | ABL1 (0.54) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1196428 | 0.84 | ABL1 (0.54) | MAPTALDH1A1KMT2AKDM4ECYP1A2 | |
| SCHEMBL7071396 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7071660 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105367-A1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | Bayer Aktiengesellschaft (DE) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010963-A1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-02 | — | — | WO | disclosed |