Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708901 | 0.81 | SLC6A2 (0.39) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL8586761 | 0.80 | ADRB3 (0.41) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL8586756 | 0.80 | ADRB3 (0.41) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7714916 | 0.78 | ADRB3 (0.40) | ADRB3ADRB1ADRB2KDM4EADRA1D | |
| SCHEMBL7714914 | 0.78 | ADRB3 (0.40) | ADRB3ADRB1ADRB2KDM4EADRA1D | |
| SCHEMBL9267480 | 0.77 | AOC3 (0.36) | S1PR3KDM4ECTSLADRA1DIDO1 | |
| SCHEMBL7708906 | 0.76 | ADRB3 (0.39) | ADRB3ADRB1ADRB2IDO1AOC3 | |
| SCHEMBL7857239 | 0.76 | KDM4E (0.34) | ADRB3ADRB1ADRB2S1PR3KDM4E | |
| SCHEMBL5949849 | 0.75 | AOC3 (0.36) | S1PR3AOC3 | |
| SCHEMBL5949847 | 0.75 | AOC3 (0.36) | S1PR3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366033-A1 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002060885-A1 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2002-08-08 | — | — | WO | disclosed |