Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069969 | 0.76 | ADRB3 (0.35) | KDM4ES1PR3MAPK1MAPTNPSR1 | |
| SCHEMBL5950226 | 0.74 | AOC3 (0.35) | KDM4ES1PR3ADRB3XPO1SMN1; SMN2 | |
| SCHEMBL7717177 | 0.72 | XPO1 (0.40) | KDM4ES1PR3ALDH1A1LMNACTSL | |
| SCHEMBL5949849 | 0.71 | AOC3 (0.36) | S1PR3SLC6A2SLC6A4XPO1SMN1; SMN2 | |
| SCHEMBL6437304 | 0.71 | AOC3 (0.36) | S1PR3SLC6A2SLC6A4XPO1SMN1; SMN2 | |
| SCHEMBL5949847 | 0.71 | AOC3 (0.36) | S1PR3SLC6A2SLC6A4XPO1SMN1; SMN2 | |
| SCHEMBL14833798 | 0.71 | SLC6A2 (0.43) | NPSR1ALDH1A1NPC1CYP2C19ADRB2 | |
| SCHEMBL7712663 | 0.71 | SLC6A2 (0.43) | NPSR1ALDH1A1NPC1CYP2C19ADRB2 | |
| SCHEMBL8613866 | 0.71 | AOC3 (0.33) | KDM4ES1PR3CTSLXPO1SMN1; SMN2 | |
| SCHEMBL4542209 | 0.69 | ACP3 (0.34) | S1PR3CYP2C19ADRB2ADRB3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082404-A2 | MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-1027418-A1 | CLEANING COMPOSITIONS CONTAINING MULTIPLY-SUBSTITUTED PROTEASE VARIANTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999020723-A9 | MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS | PROCTER & GAMBLE (US) | 1999-09-02 | — | — | WO | disclosed |
| WO-1999020723-A2 | MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-29 | — | — | WO | disclosed |
| WO-1999020727-A1 | CLEANING COMPOSITIONS CONTAINING MULTIPLY-SUBSTITUTED PROTEASE VARIANTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-29 | — | — | WO | disclosed |