Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.33 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070024 | 1.00 | HPGD (0.34) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7195888 | 0.85 | MAP1LC3B (0.42) | HPGDKDM4EALDH1A1MAPTMAP1LC3B | |
| SCHEMBL7190073 | 0.79 | KMT2A (0.35) | KDM4EMEN1KMT2AMAP1LC3BMAP1LC3A | |
| SCHEMBL6937692 | 0.79 | LMNA (0.42) | KDM4EMAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL6940113 | 0.79 | HSP90AB1 (0.36) | KDM4EMAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL6940108 | 0.79 | HSP90AB1 (0.36) | KDM4EMAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL6937333 | 0.79 | LMNA (0.40) | KDM4EMAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL7193790 | 0.78 | HSP90AB1 (0.36) | KDM4EMAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL6938077 | 0.76 | HSP90AB1 (0.46) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6938071 | 0.76 | HSP90AB1 (0.46) | HPGDKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| EP-1045856-B1 | NOVEL AROMATIC AMIDES, PREPARATION METHOD AND APPLICATION AS MEDICINES | AVENTIS PHARMA SA (FR) | 2003-04-09 | — | — | EP | disclosed |