Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | RXRA | P19793 | 4/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542294 | 0.78 | S1PR5 (0.56) | S1PR5RXRBRXRARXRGHRH3 | |
| SCHEMBL9719997 | 0.75 | RXRA (0.55) | RXRBRXRARXRGHRH3HTR7 | |
| SCHEMBL7847131 | 0.72 | RXRA (0.50) | RXRBRXRARXRGHTR7MCL1 | |
| Hydrochloric Acid SCHEMBL4496805 | 0.72 | NPY1R (0.47) | NPY1RIDO1 | |
| SCHEMBL30734997 | 0.72 | NPY1R (0.43) | NPY1RMCHR1IDO1HTR6 | |
| SCHEMBL26636104 | 0.72 | NPY1R (0.43) | NPY1RMCHR1IDO1HTR6 | |
| SCHEMBL26635881 | 0.72 | NPY1R (0.43) | NPY1RMCHR1IDO1HTR6 | |
| SCHEMBL30735107 | 0.72 | NPY1R (0.43) | NPY1RMCHR1IDO1HTR6 | |
| SCHEMBL26635886 | 0.72 | NPY1R (0.43) | NPY1RMCHR1IDO1HTR6 | |
| SCHEMBL13718669 | 0.71 | EED (0.45) | HRH3NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319004-A2 | SUBSTITUTED AZEPINO[4,5-B]INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024701-A2 | SUBSTITUTED AZEPINO[4,5B)INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |