Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345536 | 0.82 | HTT (0.41) | HTTALDH1A1MAOBPLA2G10PLA2G2A | |
| SCHEMBL295277 | 0.75 | MAOB (0.48) | MAOBPLA2G10PLA2G2ANOS1LMNA | |
| SCHEMBL4831945 | 0.73 | FFAR1 (0.46) | HTTALDH1A1LMNAHPGDMAPT | |
| SCHEMBL27640145 | 0.72 | MAOB (0.44) | MAOBPLA2G10PLA2G2ANOS1SMN1; SMN2 | |
| SCHEMBL5892305 | 0.72 | MAOB (0.44) | MAOBPLA2G10PLA2G2ANOS1LMNA | |
| Diphenylmethane SCHEMBL27952621 | 0.71 | PLA2G10 (0.61) | PLA2G10PLA2G2ALMNASMN1; SMN2KMT2A | |
| SCHEMBL442434 | 0.71 | MAOB (0.52) | ALDH1A1MAOBLMNASMN1; SMN2KMT2A | |
| SCHEMBL3063087 | 0.70 | ALDH1A1 (0.68) | ALDH1A1MITFMAOBLMNAHPGD | |
| SCHEMBL3065466 | 0.70 | RECQL (0.67) | HTTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL6162053 | 0.70 | LMNA (0.42) | HTTALDH1A1MAOBPLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |