Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16415141 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL16415177 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL3458582 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL1685969 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL7651322 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL16414653 | 1.00 | NPC1 (0.51) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL704307 | 0.98 | NPC1 (0.49) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL489809 | 0.92 | TDP1 (0.46) | NPC1JAK2RAB9APAX8KCNH2 | |
| Chloromethane SCHEMBL7281088 | 0.89 | NPC1 (0.44) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL709444 | 0.84 | TP53 (0.44) | NPC1JAK2RAB9APAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873577-B | Cycloalkenylamides as bromodomain inhibitors | 西奈山伊坎医学院 | 2019-06-18 | — | — | CN | disclosed |
| CN-109810015-A | The synthetic method of amides compound | 湖南中医药大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-109761836-A | The preparation method of amides compound | 中南大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-109503412-A | A method of amide is prepared by terminal olefin | 复旦大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-105669491-B | A kind of acylation method of amine | 苏州大学 | 2017-10-13 | — | — | CN | disclosed |
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9380782-B2 | Tetrazolinone compounds and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20150376124-A1 | ANTI-CANCER COMPOSITIONS AND METHODS | PENN STATE RES FOUND (US) | 2015-12-31 | — | — | US | disclosed |
| US-9126911-B2 | Anti-cancer compositions and methods | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-9126910-B2 | Anti-cancer compositions and methods | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-5116976-A | HINDERED AMINE LIGHT STABILIZER HYDRAZIDES | ATOCHEM NORTH AMERICA, INC (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0467344-A1 | Hindered amine light stabilizer hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0377633-A4 | PEROXIDE FREE RADICAL INITIATORS CONTAINING HINDERED AMINE LIGHT STABILIZER GROUPS | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0377633-A1 | PEROXIDE FREE RADICAL INITIATORS CONTAINING HINDERED AMINE LIGHT STABILIZER GROUPS. | PENNWALT CORP (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4925903-A | PEROXIDE CONTAINING HINDERED AMINE ALSO FUNCTIONS AS INITIATOR | PENNWALT CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |
| US-4885347-A | UNSATURATED POLYESTER | PENNWALT CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4822883-A | 2,2,6,6-TETRA SUBSTITUTED PIPERIDIN-4-YL PEROXY DERIVATIVES BECOMING CHEMICALLY BONDED TO ADDITION POLYMER | PENNWALT CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| WO-1989001474-A1 | PEROXIDE FREE RADICAL INITIATORS CONTAINING HINDERED AMINE LIGHT STABILIZER GROUPS | PENNWALT CORPORATION (US) | 1989-02-23 | — | — | WO | disclosed |
| EP-0294818-A2 | Hindered amine light stabilizers containing aromatic carboxy groups and derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1988-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376124-A1 | ANTI-CANCER COMPOSITIONS AND METHODS | MKI67, BAX, BCL2 | NPC1 1407/4885JAK2 325/4885RAB9A 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.