Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160562 | 0.97 | HCRTR1 (0.48) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7074887 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7160789 | 0.89 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL7128610 | 0.87 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL7076404 | 0.86 | KDM4E (0.44) | ALDH1A1MAPTKDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL7135775 | 0.86 | HCRTR1 (0.52) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2923794 | 0.86 | POLQ (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL12749954 | 0.82 | MAOB (0.48) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL269345 | 0.81 | KDM4E (0.52) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2929470 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4ESMN1; SMN2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051368-A1 | N-AROYL CYCLIC AMINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-26 | — | — | WO | disclosed |