Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175500 | 0.83 | NOTUM (0.33) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10554028 | 0.83 | NOTUM (0.36) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8722554 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL26617171 | 0.79 | IDO1 (0.31) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7905835 | 0.79 | TP53 (0.35) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9691797 | 0.78 | ALDH1A1 (0.38) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7929426 | 0.78 | NOTUM (0.34) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2210002 | 0.76 | IDO1 (0.33) | IDO1KDR | |
| SCHEMBL11602223 | 0.75 | NOTUM (0.44) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1799462 | 0.75 | NOTUM (0.32) | IDO1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | claimed |
| EP-0908438-B1 | Process for the preparation of 2,3,4,5-tetrafluorobenzene derivatives | BAYER AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6613948-B1 | Reacting the corresponding chlorobenzene or (chloro, fluoro)-benzene derivatives with potassium fluoride in solvent; distillation; tetrachloro benzotrifluoride, -benzoyl fluoride, or -benzonitrile as starting materials | BAYER AG (DE) | 2003-09-02 | — | — | US | disclosed |
| WO-2003055843-A1 | AGARICOGLYCERIDES AND ANALOGS | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |
| EP-0693466-B1 | Process for the preparation of aromatic fluorinated compounds and diamides | BAYER AG (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6265627-B1 | HEATING HALOGEN-CONTAINING AROMATIC COMPOUNDS WITH AN ALKALI METAL FLUORIDE IN PRESENCE OF N,N'N?-HEXA-SUBSTITUTED GUANIDINIUM HALIDE AS CATALYST TO PRODUCE POLYFLUOROAROMATIC COMPOUND | Igumnov, Sergei Mikhailovich (RU) | 2001-07-24 | — | — | US | disclosed |
| US-6114590-A | Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| US-6075165-A | Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0781747-B1 | Process for the preparation of 2,3,4,5-tetrafluoro-benzotrifluoride | BAYER AG (DE) | 1999-09-01 | — | — | EP | disclosed |
| EP-0908438-A2 | Process for the preparation of 2,3,4,5-tetrafluorobenzene derivatives | BAYER AG (DE) | 1999-04-14 | — | — | EP | disclosed |
| EP-0607824-A2 | Method for the production of multiply halogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides as well as trihalobenzotrichlorides and -benzoyl chlorides | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| US-5283378-A | Process for the dechlorination and/or debromination of fluorine-and chlorine- and/or bromine-containing aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0481317-A2 | Method for dechlorination and/or debromination of aromatic compounds containing fluorine with chlorine and/or bromine | BAYER AG (DE) | 1992-04-22 | — | — | EP | disclosed |
| US-4962246-A | INSECTICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| US-4936892-A | HERBICIDES; PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |
| EP-0313908-A2 | Halogen-substituted phenoxyphenylpropionic acid derivatives | BAYER AG (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0303118-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0302328-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302327-A1 | 3,5-Dialkyl-1-arylpyrazoles | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |