Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066871 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRDHFRELANETP53 | |
| SCHEMBL7073368 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHRDHFRELANETP53 | |
| SCHEMBL6031955 | 0.77 | ALDH1A1 (0.34) | ALDH1A1DHFRELANEGAANPSR1 | |
| SCHEMBL9242285 | 0.65 | ALDH1A1 (0.54) | ALDH1A1TSHRDHFRELANETP53 | |
| SCHEMBL27514453 | 0.63 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31306898 | 0.63 | ALDH1A1 (0.51) | ALDH1A1TSHRDHFRELANEGAA | |
| SCHEMBL30032422 | 0.63 | ALDH1A1 (0.38) | ALDH1A1TSHRELANETP53GAA | |
| SCHEMBL27865358 | 0.62 | ALDH1A1 (0.50) | ALDH1A1TSHRDHFR | |
| SCHEMBL4953794 | 0.62 | POLB (0.30) | — | |
| SCHEMBL2139487 | 0.61 | ALDH1A1 (0.49) | ALDH1A1TSHRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664353-B2 | Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-16 | — | — | US | disclosed |
| US-20030125494-A1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6479608-B1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-12 | — | — | US | disclosed |