SCHEMBL2139487

SCHEMBL2139487

CC1(C)CCCC(C)(C)N1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
DHFR P00374 7/20 0.43
TSHR P16473 2/20 0.39
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27865358 0.84 ALDH1A1 (0.50) ALDH1A1DHFRTSHR
SCHEMBL4621770 0.83 DHFR (0.43) ALDH1A1DHFR
SCHEMBL27950858 0.81 RXRA (0.43) ALDH1A1
SCHEMBL9242285 0.79 ALDH1A1 (0.54) ALDH1A1DHFRTSHR
SCHEMBL9674786 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5067477 0.78 ALDH1A1 (0.45) ALDH1A1DHFRTSHR
SCHEMBL5062027 0.78 ALDH1A1 (0.45) ALDH1A1DHFRTSHRHTR2C
SCHEMBL13412651 0.78 ALDH1A1 (0.45) ALDH1A1DHFRTSHR
SCHEMBL9440082 0.77 CARM1 (0.46) ALDH1A1DHFRTSHR
SCHEMBL17351108 0.77 ALDH1A1 (0.44) ALDH1A1DHFRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022053937-A1 PROCESS FOR PREPARING (3α,5α)-3-HYDROX Y -3-METHYL-PREGNAN -20- ONE (GANAXOLONE) INDUSTRIALE CHIMICA S.R.L. (IT) 2022-03-17 WO claimed
CN-106795250-B Process for making graft copolymers on a polyolefin backbone 博里利斯股份公司 2020-06-02 CN claimed
US-20170260312-A1 PROCESS FOR PRODUCING GRAFT COPOLYMERS ON POLYOLEFIN BACKBONE BOREALIS AG (AT) 2017-09-14 US claimed
EP-1977243-B1 HIGH OPTICAL PURITY COPOLYMER FILM ARKEMA FRANCE (FR) 2021-05-05 EP disclosed
CN-106795250-B Process for making graft copolymers on a polyolefin backbone 博里利斯股份公司 2020-06-02 CN disclosed
CN-110294842-A A kind of semiaromatic polyamide composition and its synthetic method and the polyamide moulding composition being made from it 金发科技股份有限公司 2019-10-01 CN disclosed
CN-108137929-B Resin composition, resin molded article, method for producing resin molded article with plating layer, and method for producing portable electronic device component having antenna 三菱工程塑料株式会社 2019-07-16 CN disclosed
CN-109721943-A Polyacetal resin composite 旭化成株式会社 2019-05-07 CN disclosed
CN-108586733-A A kind of Semi-aromatic polyamide resin and the polyamide moulding composition being made from it 金发科技股份有限公司 2018-09-28 CN disclosed
CN-108586732-A A kind of Semi-aromatic polyamide resin and the polyamide moulding composition being made from it 金发科技股份有限公司 2018-09-28 CN disclosed
CN-108559075-A A kind of Semi-aromatic polyamide resin and preparation method thereof and the polyamide moulding composition being made from it 金发科技股份有限公司 2018-09-21 CN disclosed
EP-1526138-A1 Process for the preparation of polyalkoxyamines or use as initiators of radical polymerizations of polyfunctional living polymers ARKEMA (FR) 2005-04-27 EP disclosed
EP-1311472-B1 METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES ATOFINA (FR) 2004-10-20 EP disclosed
US-6700007-B2 IN A BIPHASIC MEDIUM, BY MIXING AN IONIC LIQUID SUCH AS AN ALKYLIMIDAZOLIUM HALIDE, AN ORGANIC SOLVENT, A TRANSITION METAL SALT, A METAL LIGAND, A HALOHYDROCARBON AND A NITROXIDE ATOFINA (FR) 2004-03-02 US disclosed
US-6657043-B1 Free-radical polymerization initiators; polyalkoxyamines with phosphine derivative substituents ATOFINA (FR) 2003-12-02 US disclosed
US-6569967-B1 Using polymerization catalyst ATOFINA (FR) 2003-05-27 US disclosed
US-20030050507-A1 Method for prepararing alkoxyamines from nitroxides ATOFINA (FR) 2003-03-13 US disclosed
EP-1086073-B1 METHOD FOR PREPARING ALKOXYAMINES FROM NITROXIDES ATOCHEM ELF SA (FR) 2003-03-12 EP disclosed
US-6495720-B1 PREPARING TRISUBSTITUTED HYDROXYLAMINES, OBTAINED FROM NITROXIDES, WHICH CAN BE USED IN PARTICULAR AS RADICAL-POLYMERIZATION INITIATORS ATOFINA (FR) 2002-12-17 US disclosed
EP-1153030-B1 ALKOXYAMINES DERIVED FROM NITROXIDES BETA PHOSPHORYLATED, THEIR USE FOR RADICAL POLYMERISATION ATOFINA (FR) 2002-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030050507-A1 Method for prepararing alkoxyamines from nitroxides ZYX, ZFX, PNMT ALDH1A1 3105/4885DHFR 3527/4885TSHR 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.