Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.34 |
| ▸ | ITGAV | P06756 | 5/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.34 |
| ▸ | ITGAL | P20701 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 5/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.33 |
| ▸ | PROC | P04070 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7076704 | 1.00 | ITGB3 (0.34) | ITGB3ITGAVITGB1ITGA5ITGB2 | |
| Trifluoroacetic Acid SCHEMBL7071717 | 0.99 | ITGB3 (0.35) | ITGB3ITGAVITGB1ITGA5ITGB2 | |
| SCHEMBL7071473 | 0.87 | — | — | |
| SCHEMBL7076718 | 0.87 | — | — | |
| SCHEMBL7071731 | 0.86 | KDM4E (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL7078541 | 0.86 | ITGB3 (0.41) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL7073315 | 0.85 | ALDH1A1 (0.35) | — | |
| SCHEMBL7076630 | 0.85 | ALDH1A1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL7077479 | 0.84 | ITGB3 (0.32) | ITGB3ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL7077484 | 0.84 | ITGB3 (0.32) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | claimed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | claimed |
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | ITGB3 3/4885ITGAV 1/4885ITGB1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.