SCHEMBL7071497

SCHEMBL7071497

CC(C)(C)NN=C(C(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.49
GAA P10253 2/20 0.44
CYP2C19 P33261 2/20 0.44
MAPT P10636 3/20 0.43
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 1/20 0.43
GLA P06280 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
CYP2C9 P11712 2/20 0.41
EPHX1 P07099 1/20 0.41
LMNA P02545 1/20 0.40
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564185 0.84 SMN1; SMN2 (0.47) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL11572214 0.79 POLB (0.53) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL11482485 0.79 POLB (0.53) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL11482477 0.79 POLB (0.53) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL6546527 0.75 POLB (0.55) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL9461030 0.74 TSHR (0.44) POLBMAPTALDH1A1SMN1; SMN2CYP2C9
SCHEMBL23950032 0.73 POLB (0.81) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL11479747 0.73 POLB (0.51) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL21283604 0.73 POLB (0.51) POLBGAACYP2C19MAPTALDH1A1
SCHEMBL24433675 0.73 GAA (0.47) POLBGAAMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200393-B1 OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2003-12-10 EP disclosed
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity MONSANTO TECHNOLOGY LLC. 2002-04-18 US disclosed
US-6359156-B1 CONTROLLING DISEASES IN CEREAL PLANTS MONSANTO TECHNOLOGY LLC 2002-03-19 US disclosed
US-6297271-B1 CONTROLLING TAKE-ALL DISEASE IN A PLANT MONSANTO TECHNOLOGY LLC 2001-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity AADAC, HAAO, OGA POLB 2888/4885GAA 36/4885CYP2C19 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.