Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479747 | 1.00 | POLB (0.51) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL10719307 | 1.00 | POLB (0.51) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL21283603 | 0.86 | MAPT (0.45) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL9917542 | 0.86 | MAPT (0.53) | MAPTALDH1A1RAB9AKMT2AGAA | |
| SCHEMBL13219034 | 0.85 | MAPT (0.53) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL4549462 | 0.84 | MAPT (0.45) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL11775964 | 0.83 | MAPT (0.47) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL10333091 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1RAB9AKMT2AGAA | |
| SCHEMBL17655224 | 0.80 | KMT2A (0.58) | POLBMAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL24270752 | 0.78 | MAPT (0.46) | POLBMAPTALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | DARTMOUTH COLLEGE (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256472-A1 | PHOTOCHROMIC HYDRAZONE SWITCHES | CRYZ, PIN1, PPOX | POLB 1914/4885MAPT 702/4885ALDH1A1 404/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | POLB 1914/4885MAPT 702/4885ALDH1A1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.