Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071497 | 0.84 | POLB (0.49) | SMN1; SMN2TSHRSRCGAACYP2C19 | |
| SCHEMBL10333091 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2TSHRSRCGAAALDH1A1 | |
| SCHEMBL6703692 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2TSHRCYP2C19ALDH1A1MAPT | |
| SCHEMBL5797662 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2TSHRCYP2C19ALDH1A1MAPT | |
| SCHEMBL6025442 | 0.77 | GAA (0.57) | SMN1; SMN2TSHRSRCGAACYP2C19 | |
| SCHEMBL6157370 | 0.77 | GAA (0.57) | SMN1; SMN2TSHRSRCGAACYP2C19 | |
| SCHEMBL6025444 | 0.77 | GAA (0.57) | SMN1; SMN2TSHRSRCGAACYP2C19 | |
| SCHEMBL9461030 | 0.77 | TSHR (0.44) | SMN1; SMN2TSHRSRCALDH1A1MAPT | |
| SCHEMBL6932293 | 0.77 | TSHR (0.44) | SMN1; SMN2TSHRSRCGAACYP2C19 | |
| SCHEMBL21884118 | 0.75 | TSHR (0.50) | SMN1; SMN2TSHRSRCGAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200393-A1 | OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY | Monsanto Technology LLC (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012590-A1 | OXYME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY | MONSANTO TECHNOLOGY LLC (US) | 2001-02-22 | — | — | WO | disclosed |