Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071713 | 1.00 | ABL1 (0.54) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL7068592 | 0.88 | ALDH1A1 (0.48) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL1196433 | 0.88 | ABL1 (0.54) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL7068587 | 0.88 | ALDH1A1 (0.48) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL1196428 | 0.88 | ABL1 (0.54) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL7770050 | 0.84 | MAPT (0.44) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL30970424 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTCYP1A2CYP2C19 | |
| SCHEMBL16960449 | 0.81 | ABL1 (0.60) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL2420654 | 0.81 | ABL1 (0.60) | ABL1ALDH1A1HPGDMAPTCYP1A2 | |
| SCHEMBL3167942 | 0.80 | MAPT (0.49) | ABL1ALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105367-B1 | SUBSTITUTED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS | BAYER AG (DE) | 2003-06-18 | — | — | EP | claimed |
| US-6455725-B1 | Substituted cinnamic acids and cinnamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | claimed |
| US-6455725-B1 | Substituted cinnamic acids and cinnamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |