Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611956 | 0.90 | MAPT (0.72) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL1306598 | 0.89 | MAPT (0.61) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL7072156 | 0.88 | MAPT (0.70) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL11571840 | 0.84 | MAPT (0.86) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL11827090 | 0.82 | MAPT (0.72) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL31000396 | 0.82 | MAPT (0.72) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL31358138 | 0.82 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAGAAMEN1 | |
| SCHEMBL11795244 | 0.82 | ALDH1A1 (0.59) | MAPTALDH1A1LMNAGAAMEN1 | |
| SCHEMBL12112128 | 0.81 | MAPT (0.61) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL31384417 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219718-A1 | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same | UNIVERSITY OF MARYLAND, BALTIMORE | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030219718-A1 | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same | TP53, S100P, S100A4 | MAPT 1570/4885ALDH1A1 3844/4885LMNA 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.