Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroethane SCHEMBL4603454 | 0.94 | TSHR (0.86) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL64609 | 0.87 | — | — | |
| Trichloroethane SCHEMBL10482068 | 0.87 | TSHR (1.00) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL3833855 | 0.87 | TSHR (1.00) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL16434 | 0.87 | — | — | |
| Trichloroethane SCHEMBL25372481 | 0.80 | — | — | |
| Trichloroethane SCHEMBL11347390 | 0.80 | — | — | |
| Trichloroethane SCHEMBL8720047 | 0.80 | — | — | |
| Trichloroethane SCHEMBL8720044 | 0.80 | TSHR (0.86) | TSHRALDH1A1LMNACYP2E1THRB | |
| Trichloroethane SCHEMBL8326914 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368499-A2 | RAT TOXICOLOGICALLY RELEVANT GENES AND USES THEREOF | Phase-1 Molecular Toxicology Inc. (US) | 2003-12-10 | — | — | EP | claimed |
| WO-2002066682-A2 | RAT TOXICOLOGICALLY RELEVANT GENES AND USES THEREOF | PHASE-1 MOLECULAR TOXICOLOGY, INC. (US) | 2002-08-29 | — | — | WO | claimed |