Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83099 | 0.81 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL29193898 | 0.77 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL8994166 | 0.76 | — | — | |
| SCHEMBL28228911 | 0.72 | — | — | |
| SCHEMBL27454769 | 0.68 | ALDH1A1 (0.34) | ALDH1A1CYP3A4HPGDHSD17B10TDP1 | |
| SCHEMBL7263398 | 0.67 | CYP3A4 (0.40) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL17274422 | 0.65 | HTR6 (0.38) | — | |
| SCHEMBL7265796 | 0.64 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL5935478 | 0.63 | ALDH1A1 (0.60) | ABCB11ALDH1A1NR3C1CYP1A2CYP3A4 | |
| SCHEMBL15055886 | 0.62 | ALDH1A1 (0.30) | ALDH1A1CYP1A2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030119028-A1 | Device and methods for enhanced microarray hybridization reactions | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2003-06-26 | — | — | US | disclosed |
| US-20030099930-A1 | Novel method to enhance microarray surface density and hybridization efficiency | GRAVES DAVID J (US) | 2003-05-29 | — | — | US | disclosed |