Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.30 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071278 | 0.80 | PPARD (0.34) | ITGB3ITGA2BPPARD | |
| Hydrochloric Acid SCHEMBL7071485 | 0.79 | ITGB3 (0.34) | ITGB3ITGA2BPPARD | |
| SCHEMBL7073042 | 0.77 | ITGB3 (0.36) | ITGB3ITGA2BPPARD | |
| SCHEMBL7073029 | 0.76 | PPARD (0.34) | ITGB3ITGA2BPPARD | |
| SCHEMBL7073055 | 0.76 | ITGB3 (0.33) | ITGB3ITGA2BPPARD | |
| SCHEMBL7075936 | 0.72 | KDR (0.32) | — | |
| SCHEMBL7075186 | 0.72 | PDE3B (0.33) | — | |
| SCHEMBL7073142 | 0.69 | XIAP (0.42) | ITGB3ITGA2B | |
| SCHEMBL7076035 | 0.67 | LMNA (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL7071326 | 0.66 | ITGB3 (0.36) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | claimed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | claimed |
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | ITGB3 3/4885ITGA2B 7/4885F2 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.