Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558899 | 0.89 | THRA (0.87) | THRATHRB | |
| SCHEMBL7073438 | 0.88 | THRA (0.67) | THRATHRB | |
| SCHEMBL7643749 | 0.82 | THRB (0.58) | THRATHRB | |
| SCHEMBL5281917 | 0.82 | THRA (0.78) | THRATHRB | |
| SCHEMBL282382 | 0.82 | THRA (1.00) | THRATHRB | |
| SCHEMBL29373235 | 0.82 | THRA (1.00) | THRATHRB | |
| SCHEMBL19057792 | 0.82 | THRB (0.82) | THRATHRB | |
| SCHEMBL7073126 | 0.80 | THRA (0.76) | THRATHRB | |
| SCHEMBL282637 | 0.80 | THRB (0.54) | THRATHRB | |
| SCHEMBL4964368 | 0.77 | THRB (0.63) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000008-B1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KAROBIO AB (SE) | 2003-06-25 | — | — | EP | disclosed |
| US-6465687-B1 | SUBSTITUTED 4-HYDROXY-3-ALKYL- OR CYCLOALKYL-PHENOXYBENZENE COMPOUNDS SUCH AS 3,5-DIBROMO-4-(4-HYDROXY-3-ISOPROPYLPHENOXY)BENZOIC ACID, EXPRESSION INHIBITION OF A T3 REGULATED GENE | KARO BIO AB (SE) | 2002-10-15 | — | — | US | disclosed |
| EP-1000008-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999000353-A1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KARO BIO AB (SE) | 1999-01-07 | — | — | WO | disclosed |