SCHEMBL7073223

SCHEMBL7073223

Cc1cc(C)c(C(=O)C(C(=O)c2c(C)cc(C)cc2C)C(C)(C)CC(C)CP)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5160078 0.85 L3MBTL1 (0.31) L3MBTL1
SCHEMBL611536 0.83 KDM4E (0.35) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5995538 0.77 HPGD (0.36) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL131005 0.73 CA12 (0.41) LMNAKMT2ASMN1; SMN2
SCHEMBL27467986 0.69 KDM4E (0.36) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5146644 0.68 KDM4E (0.38) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5997084 0.68 HPGD (0.43) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL10019207 0.67 FFAR1 (0.50) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL7073220 0.67 L3MBTL1 (0.38) KDM4EL3MBTL1HPGDNPSR1MCOLN3
SCHEMBL5994795 0.67 RXRB (0.31) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066335-B1 SULPHUR PRODUCTS FOR ADDING A POLYTHIOL ON A NORBORNENE DERIVATIVE, PREPARATION METHOD AND USE FOR OBTAINING RADICAL CROSS-LINKING PRODUCTS CRAY VALLEY SA (FR) 2003-07-02 EP disclosed
EP-1234201-A1 METHOD FOR MANUFACTURING OPTICAL FIBER RIBBON ALCATEL (FR) 2002-08-28 EP disclosed
WO-2001033275-A1 METHOD FOR MANUFACTURING OPTICAL FIBER RIBBON ALCATEL (FR) 2001-05-10 WO disclosed