Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490454 | 0.74 | GAA (0.56) | GRIN2BPIM1FLT3GAAMAPT | |
| SCHEMBL4742061 | 0.74 | GAA (0.56) | GRIN2BPIM1FLT3GAAMAPT | |
| SCHEMBL10781695 | 0.74 | ALDH1A1 (0.41) | KMT2AMEN1NPC1MAPTRYR2 | |
| SCHEMBL11178198 | 0.74 | MAPT (0.52) | KMT2AMEN1GAAMAPTSLC18A3 | |
| SCHEMBL19871777 | 0.73 | — | — | |
| SCHEMBL30873011 | 0.72 | MAPT (0.45) | KMT2AMEN1NPC1MAPTCYP19A1 | |
| SCHEMBL10585357 | 0.72 | RYR2 (0.37) | KMT2AMEN1NPC1GAARYR2 | |
| SCHEMBL6444678 | 0.72 | RYR2 (0.37) | KMT2AMEN1NPC1GAAMAPT | |
| SCHEMBL8822493 | 0.72 | PLAU (0.45) | KMT2AMEN1NPC1GAASIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL8090454 | 0.72 | GAA (0.54) | GRIN2BPIM1FLT3GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065008-A1 | Selective estrogen receptor modulators in combination with estrogens | ENDORECHERCHE, INC. | 2003-04-03 | — | — | US | claimed |
| US-20020198179-A1 | Selective estrogen receptor modulators in combination with estrogens | ENDORECHERCHE, INC. | 2002-12-26 | — | — | US | claimed |
| EP-1251855-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS IN COMBINATION WITH ESTROGENS | Endorecherche, Inc. (CA) | 2002-10-30 | — | — | EP | claimed |
| WO-2001054699-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS IN COMBINATION WITH ESTROGENS | ENDORECHERCHE, INC. (CA) | 2001-08-02 | — | — | WO | claimed |
| US-4801593-A | VIRICIDE FOR RHINITIS VIRUS CONTAINING 2-PHENYLTETRALIN DERIVATIVE | BURROUGHS WELLCOME CO. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0025598-B1 | THE USE OF 2-PHENYLTETRALIN DERIVATIVES, OR HETEROCYCLIC ANALOGUES, IN MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065008-A1 | Selective estrogen receptor modulators in combination with estrogens | ESR1, BRCA1, KISS1R | KMT2A 691/4885MEN1 54/4885NPC1 1261/4885 |
| US-20020198179-A1 | Selective estrogen receptor modulators in combination with estrogens | KISS1R, ESR1, BRCA1 | KMT2A 716/4885MEN1 48/4885NPC1 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.