Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | THRA | P10827 | 6/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073304 | 1.00 | THRB (0.48) | THRBTHRATNFRSF1AFDPSMAOB | |
| SCHEMBL282456 | 0.90 | FDPS (0.50) | THRBTHRAFDPSMAOBESR1 | |
| SCHEMBL2170309 | 0.85 | THRB (0.46) | THRBTHRATNFRSF1ARORCLMNA | |
| SCHEMBL16496217 | 0.85 | THRB (0.46) | THRBTHRATNFRSF1ARORCLMNA | |
| SCHEMBL16496152 | 0.82 | THRB (0.46) | THRBTHRATNFRSF1ARORCKDM4E | |
| SCHEMBL2172723 | 0.82 | THRB (0.46) | THRBTHRATNFRSF1ARORCKDM4E | |
| SCHEMBL2171186 | 0.81 | THRB (0.44) | THRBTHRATNFRSF1ARORCLMNA | |
| SCHEMBL16495821 | 0.81 | THRB (0.44) | THRBTHRATNFRSF1ARORCLMNA | |
| SCHEMBL2169387 | 0.80 | THRB (0.44) | THRBTHRATNFRSF1ARORCLMNA | |
| SCHEMBL8892251 | 0.80 | THRB (0.51) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000008-B1 | NOVEL THYROID RECEPTOR LIGANDS AND METHOD | KAROBIO AB (SE) | 2003-06-25 | — | — | EP | disclosed |