SCHEMBL7073369

SCHEMBL7073369

CC(C)COC(=O)[C@H](CO)NC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.47
CTSS P25774 6/20 0.47
CTSL P07711 2/20 0.47
CTSB P07858 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CAPN1 P07384 1/20 0.41
CYP2D6 P10635 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13640515 0.88 CTSK (0.43) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL29251195 0.86 CTSK (0.46) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL21664014 0.86 CTSK (0.46) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL29251120 0.86 CTSK (0.46) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL23788080 0.86 CTSK (0.46) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL24985078 0.86 CTSK (0.46) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL20095049 0.85 CTSK (0.49) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL11173165 0.84 CYP1A2 (0.48) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL2531297 0.84 CYP1A2 (0.48) CTSKCTSSCTSLCTSBCYP1A2
SCHEMBL1846647 0.84 CYP1A2 (0.48) CTSKCTSSCTSLCTSBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003053218-A2 IMPLANT COATINGS THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO (US) 2003-07-03 WO disclosed