Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706118 | 0.89 | CTSK (0.52) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL7073369 | 0.88 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL14654976 | 0.81 | TDP1 (0.47) | CTSKCTSSCA1CA2GAA | |
| SCHEMBL13086767 | 0.80 | CTSS (0.57) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL11173165 | 0.80 | CYP1A2 (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL1846647 | 0.80 | CYP1A2 (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL2531297 | 0.80 | CYP1A2 (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL21096417 | 0.79 | CTSK (0.42) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL17706125 | 0.78 | CTSK (0.58) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL3617926 | 0.78 | CYP1A2 (0.47) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829226-B2 | Lacosamide intermediate compound, preparation method thereof and use thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2014-09-09 | — | — | US | disclosed |
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2013-03-14 | — | — | US | disclosed |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSK 1040/4885CTSS 590/4885CTSL 1174/4885 |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSK 1040/4885CTSS 590/4885CTSL 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.