Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530645 | 0.79 | FOLH1 (0.43) | FOLH1 | |
| Glycerylphosphate SCHEMBL2593674 | 0.74 | ALDH1A1 (0.43) | ALDH1A1FKBP5 | |
| Malic Acid SCHEMBL1646346 | 0.73 | SMN1; SMN2 (0.54) | ALDH1A1FKBP5 | |
| Pyrophosphoric Acid SCHEMBL17260502 | 0.73 | ALDH1A1 (0.50) | ALDH1A1FKBP5 | |
| Phosphoric Acid SCHEMBL28458516 | 0.72 | ALDH1A1 (0.54) | ALDH1A1FKBP5 | |
| Aspartic Acid SCHEMBL28155193 | 0.72 | ALDH1A1 (0.45) | ALDH1A1FKBP5 | |
| Fosfonet SCHEMBL15510601 | 0.72 | MEN1 (0.52) | ALDH1A1FKBP5 | |
| Pyrophosphoric Acid SCHEMBL17216548 | 0.70 | ALDH1A1 (0.56) | ALDH1A1FKBP5 | |
| Pyrophosphoric Acid SCHEMBL8011246 | 0.70 | ALDH1A1 (0.56) | ALDH1A1FKBP5 | |
| Bromoacetic Acid SCHEMBL16859465 | 0.70 | ALDH1A1 (0.56) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003054180-A1 | MODIFIED MEK1 AND MEK2, CRYSTAL OF A PEPTIDE: LIGAND: COFACTOR COMPLEX CONTAINING SUCH MODIFIED MEK1 OR MEK2, AND METHODS OF USE THEREOF | WARNER-LAMBERT COMPANY LLC (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1321518-A1 | Modified MEK1 and MEK2, crystal of a peptide: ligand: cofactor complex containing such modified MEK1 or MEK2, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2003-06-25 | — | — | EP | disclosed |