Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL17216548

O=P(O)(O)OP(=O)(O)O.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.56

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
FKBP5 Q13451 1/20 0.56
FDPS P14324 1/20 0.43
BLM P54132 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL8011246 1.00 ALDH1A1 (0.56) ALDH1A1FKBP5FDPSBLMTDP1
Pyrophosphoric Acid SCHEMBL2482818 1.00 ALDH1A1 (0.56) ALDH1A1FKBP5FDPSBLMTDP1
Pyrophosphoric Acid SCHEMBL28838063 0.98 ALDH1A1 (0.54) ALDH1A1FKBP5FDPSBLMTDP1
Pyrophosphoric Acid SCHEMBL17260502 0.94 ALDH1A1 (0.50) ALDH1A1FKBP5FDPSBLMTDP1
Triphosphate SCHEMBL22659158 0.92 ALDH1A1 (0.52) ALDH1A1FKBP5FDPSBLMTDP1
Imidazole SCHEMBL29042475 0.90 ALDH1A1 (0.50) ALDH1A1FKBP5FDPSBLMTDP1
Pyrophosphoric Acid SCHEMBL28404443 0.86 ALDH1A1 (0.42) ALDH1A1FKBP5FDPSBLMTDP1
Phosphoric Acid SCHEMBL1352614 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Phosphoric Acid SCHEMBL1090914 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Phosphoric Acid SCHEMBL22659156 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026414-B P1,P4Two(Uridine 5 ')The manufacture method of four phosphates YAMASA 酱油株式会社 2017-06-23 CN claimed
US-11208428-B2 Method for producing P1,P4-di(uridine 5′-) tetraphosphate YAMASA CORPORATION (JP) 2021-12-28 US disclosed
CN-110590887-B Preparation method of phosphate 江苏金殳医药科技有限公司 2020-12-15 CN disclosed
CN-106928269-B Preparation method of phosphate 长春普华制药股份有限公司 2020-03-24 CN disclosed
CN-110590887-A Preparation method of phosphate 南京帝昌医药科技有限公司 2019-12-20 CN disclosed
US-20190092803-A1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-) TETRAPHOSPHATE YAMASA CORPORATION (JP) 2019-03-28 US disclosed
US-10179799-B2 Method for producing P1,P4-di(uridine 5′-) tetraphosphate YAMASA CORPORATION (JP) 2019-01-15 US disclosed
CN-106928269-A A kind of preparation method of phosphate 长春普华制药股份有限公司 2017-07-07 CN disclosed
CN-105026414-B P1,P4Two(Uridine 5 ')The manufacture method of four phosphates YAMASA 酱油株式会社 2017-06-23 CN disclosed
EP-2940030-B1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-)TETRAPHOSPHATE YAMASA CORP (JP) 2017-06-14 EP disclosed
US-20160194347-A1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-) TETRAPHOSPHATE YAMASA CORPORATION (JP) 2016-07-07 US disclosed
EP-2940030-A1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-)TETRAPHOSPHATE YAMASA CORPORATION (JP) 2015-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092803-A1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-) TETRAPHOSPHATE UPP1, UMPS, UGP2 ALDH1A1 1776/4885FKBP5 3085/4885FDPS 156/4885
US-11208428-B2 Method for producing P1,P4-di(uridine 5′-) tetraphosphate UPP1, UMPS, UGP2 ALDH1A1 1779/4885FKBP5 3103/4885FDPS 155/4885
US-20160194347-A1 METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-) TETRAPHOSPHATE UPP1, UMPS, UGP2 ALDH1A1 1776/4885FKBP5 3085/4885FDPS 156/4885
US-10179799-B2 Method for producing P1,P4-di(uridine 5′-) tetraphosphate UPP1, UMPS, UGP2 ALDH1A1 1779/4885FKBP5 3103/4885FDPS 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.