SCHEMBL7073576

SCHEMBL7073576

COC(=CC(=O)Cl)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
F2 P00734 1/20 0.43
LMNA P02545 1/20 0.43
KMT2A Q03164 5/20 0.43
MEN1 O00255 3/20 0.43
SLC6A3 Q01959 1/20 0.42
SRC P12931 1/20 0.42
RAB9A P51151 4/20 0.41
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 2/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15880803 1.00 TSHR (0.55) TSHRF2LMNAKMT2AMEN1
SCHEMBL16403663 0.84 TSHR (0.59) TSHRF2LMNAKMT2AMEN1
SCHEMBL3189100 0.84 TSHR (0.59) TSHRF2LMNAKMT2AMEN1
SCHEMBL1536367 0.84 TSHR (0.59) TSHRF2LMNAKMT2AMEN1
SCHEMBL1536368 0.84 TSHR (0.59) TSHRF2LMNAKMT2AMEN1
SCHEMBL1137903 0.82 TSHR (0.57) TSHRF2LMNAKMT2AMEN1
SCHEMBL14852715 0.82 TSHR (0.57) TSHRF2LMNAKMT2AMEN1
SCHEMBL13148534 0.81 TSHR (0.52) TSHRF2LMNAKMT2AMEN1
SCHEMBL13183413 0.80 TSHR (0.50) TSHRF2LMNAKMT2AMEN1
SCHEMBL1695604 0.78 TSHR (0.52) TSHRF2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651253-B Phenylpropanoid ester derivative and application thereof as neuroprotective medicament 上海医药工业研究院 2022-03-25 CN disclosed
EP-0945764-B1 Photoresist composition SUMITOMO CHEMICAL CO (JP) 2003-06-18 EP disclosed
US-6258507-B1 UNSATURATED AROMATIC ACRYLATED ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-10 US disclosed
EP-0945764-A2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-29 EP disclosed