Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208525 | 0.89 | MEN1 (0.60) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7162258 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL38660692 | 0.69 | MEN1 (0.76) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6231890 | 0.69 | ALDH1A1 (0.55) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6685738 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6235030 | 0.69 | HSD17B10 (0.75) | KDM4EALDH1A1HTTLMNAHPGD | |
| SCHEMBL8244097 | 0.68 | EGLN1 (0.69) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27854528 | 0.68 | MEN1 (0.74) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7435419 | 0.67 | KDM4E (0.72) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6232527 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |