Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232527 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL6208525 | 0.79 | MEN1 (0.60) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL25733860 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL29574988 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8244097 | 0.74 | EGLN1 (0.69) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL7135259 | 0.74 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL6690224 | 0.71 | DAO (0.58) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL3930634 | 0.71 | MAPK1 (0.55) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL6234246 | 0.71 | MAPK1 (0.52) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL7162258 | 0.70 | KDM4E (0.47) | ALDH1A1KDM4EKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |