Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901332 | 1.00 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL726240 | 0.75 | KDM1A (0.43) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL10618931 | 0.75 | SLC6A4 (0.41) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL4371896 | 0.72 | SLC6A2 (0.62) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL4369356 | 0.72 | SLC6A4 (0.53) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL11840906 | 0.72 | ATP1A1 (0.40) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL9006877 | 0.72 | KDM1A (0.42) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL22579672 | 0.71 | SLC6A2 (0.65) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL7531306 | 0.71 | SLC6A4 (0.73) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 | |
| SCHEMBL4372937 | 0.71 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1SLC22A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940385-B1 | Process for the separation of the (RR,SS)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)-cyclohexanol isomer from the (RS,SR) isomer by selective precipitation | DINAMITE DIPHARMA S P A (IT) | 2003-06-25 | — | — | EP | disclosed |