Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518984 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL3518987 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL3519584 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL3519583 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL3518982 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL4398580 | 0.82 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL11078094 | 0.82 | SLC6A4 (0.52) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL4394653 | 0.82 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL4391875 | 0.82 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 | |
| SCHEMBL11078071 | 0.80 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2OPRM1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187804-A1 | METHOD FOR SEPARATING THE DIASTEREOMER BASES OF 2- (DIMETHYLAMINO)METHYL]-1-(3-METHOXYPHENYL)-CYCLOHEXANOL | Grünenthal GmbH (DE) | 2002-03-20 | — | — | EP | disclosed |
| US-20010006967-A1 | METHOD OF SIMULTANEOUSLY ENHANCING ANALGESIC POTENCY AND ATTENUATING ADVERSE SIDE EFFECTS CAUSED BY TRAMADOL AND OTHER BIMODALLY-ACTING OPIOID AGONISTS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A CORP. OF NEW YORK | 2001-07-05 | — | — | US | disclosed |
| WO-2000078705-A1 | METHOD FOR SEPARATING THE DIASTEREOMER BASES OF 2-[(DIMETHYLAMINO)METHYL]-1-(3-METHOXYPHENYL)-CYCLOHEXANOL | Grünenthal GmbH (DE) | 2000-12-28 | — | — | WO | disclosed |