Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | PLG | P00747 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27530030 | 0.97 | F10 (0.59) | F10KMT2AATMALDH1A1PLG | |
| SCHEMBL7076717 | 0.90 | F10 (0.60) | F10KMT2A | |
| Acetic Acid SCHEMBL27525139 | 0.88 | F10 (0.57) | F10KMT2A | |
| SCHEMBL5735860 | 0.87 | F10 (0.80) | F10KMT2AATMALDH1A1PLG | |
| Acetic Acid SCHEMBL28744428 | 0.85 | F10 (0.74) | F10KMT2AATMALDH1A1PKM | |
| SCHEMBL7074277 | 0.85 | F10 (0.67) | F10KMT2AATMALDH1A1PLG | |
| SCHEMBL5735399 | 0.84 | KMT2A (0.62) | F10KMT2AATMALDH1A1PKM | |
| Acetic Acid SCHEMBL27550441 | 0.84 | F10 (0.62) | F10KMT2AATMALDH1A1PLG | |
| SCHEMBL7074873 | 0.81 | LMNA (0.48) | F10KMT2AALDH1A1PLGSMN1; SMN2 | |
| Acetic Acid SCHEMBL27550401 | 0.79 | LMNA (0.46) | F10KMT2AALDH1A1PLGPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |