Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PLG | P00747 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27550441 | 0.96 | F10 (0.62) | F10ATMSMN1; SMN2PLGGAA | |
| SCHEMBL5735860 | 0.91 | F10 (0.80) | F10ATMSMN1; SMN2PLGGAA | |
| SCHEMBL7074239 | 0.90 | F10 (0.63) | F10ATMSMN1; SMN2PLGCA12 | |
| Acetic Acid SCHEMBL28744428 | 0.87 | F10 (0.74) | F10ATMSMN1; SMN2GAAPKM | |
| Acetic Acid SCHEMBL27550419 | 0.87 | F10 (0.59) | F10ATMSMN1; SMN2PLG | |
| SCHEMBL7075851 | 0.85 | USP2 (0.61) | F10SMN1; SMN2PLGGAAPKM | |
| SCHEMBL7074137 | 0.85 | F10 (0.62) | F10ATMSMN1; SMN2PLGGAA | |
| SCHEMBL7071911 | 0.84 | L3MBTL1 (0.61) | F10GAAKMT2AMEN1CA12 | |
| SCHEMBL7074160 | 0.83 | F10 (0.54) | F10SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL7074108 | 0.83 | F10 (0.54) | F10SMN1; SMN2GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |