Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074203 | 1.00 | TP53 (0.66) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL211524 | 0.87 | AKR1C3 (0.56) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL2914673 | 0.87 | AKR1C3 (0.56) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL3716652 | 0.87 | AKR1C3 (0.56) | TP53MEN1POLBKMT2AHDAC2 | |
| Hydrochloric Acid SCHEMBL6818657 | 0.85 | AKR1C3 (0.54) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL28493126 | 0.80 | TP53 (0.51) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL4222609 | 0.80 | TP53 (0.44) | TP53MEN1POLBKMT2AHDAC6 | |
| SCHEMBL4222611 | 0.80 | TP53 (0.44) | TP53MEN1POLBKMT2AHDAC6 | |
| SCHEMBL8516515 | 0.80 | AKR1C3 (0.48) | TP53MEN1POLBKMT2AHDAC2 | |
| SCHEMBL7072091 | 0.79 | NPC1 (0.47) | TP53MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946492-B1 | NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF | BAYER CROPSCIENCE GMBH (DE) | 2003-06-18 | — | — | EP | claimed |
| CN-111592519-B | Fluorine-containing carboxylic acid compound and preparation method thereof | 四川大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-111592519-A | Fluorine-containing carboxylic acid compound and preparation method thereof | 四川大学 | 2020-08-28 | — | — | CN | disclosed |