Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716652 | 1.00 | AKR1C3 (0.56) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL2914673 | 1.00 | AKR1C3 (0.56) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL6818657 | 0.98 | AKR1C3 (0.54) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL8516515 | 0.92 | AKR1C3 (0.48) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL7074200 | 0.87 | TP53 (0.66) | AKR1C3AKR1C1TP53HTTTSHR | |
| SCHEMBL7074203 | 0.87 | TP53 (0.66) | AKR1C3AKR1C1TP53HTTTSHR | |
| SCHEMBL11179955 | 0.86 | AKR1C3 (0.50) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL11179967 | 0.86 | AKR1C3 (0.50) | AKR1C3AKR1C1CYP2C9CYP3A4TP53 | |
| SCHEMBL19712515 | 0.85 | ALDH1A1 (0.46) | AKR1C3AKR1C1CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL19712514 | 0.85 | ALDH1A1 (0.46) | AKR1C3AKR1C1CYP2C9CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594675-B | Beta-carbalin-cinnamic acid skeleton derivative and preparation method and application thereof | 西安医学院 | 2024-01-30 | — | — | CN | claimed |
| CN-117199530-A | Sodium ion battery electrolyte additive adaptive to hard carbon material and application thereof | 泰安市法拉第能源科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116589458-A | Co-crystals of berberine-substituted cinnamic acid and application thereof in preparation of medicines for treating colonitis | 安徽中医药大学 | 2023-08-15 | — | — | CN | claimed |
| CN-115594675-A | Beta-carbalin-cinnamic acid skeleton derivative and preparation method and application thereof | 西安医学院（CN） | 2023-01-13 | — | — | CN | claimed |
| US-8089585-B2 | Optical film, preparation method of the same, and liquid crystal display comprising the same | LG CHEM, LTD. (KR) | 2012-01-03 | — | — | US | claimed |
| US-20100182547-A1 | Optical film, preparation method of the same, and liquid crystal display comprising the same | LG CHEM, LTD. (KR) | 2010-07-22 | — | — | US | claimed |
| US-7732625-B2 | Colorant compounds | XEROX CORPORATION (US) | 2010-06-08 | — | — | US | claimed |
| US-7311767-B2 | Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | claimed |
| EP-1747059-A1 | PERVAPORATION COMPOSITE MEMBRANES | McMaster University (CA) | 2007-01-31 | — | — | EP | claimed |
| US-7033424-B2 | Phase change inks | XEROX CORPORATION (US) | 2006-04-25 | — | — | US | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| US-20040147493-A1 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2004-07-29 | — | — | US | claimed |
| US-20030166621-A1 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2003-09-04 | — | — | US | claimed |
| EP-0946492-B1 | NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF | BAYER CROPSCIENCE GMBH (DE) | 2003-06-18 | — | — | EP | claimed |
| US-5972839-A | MIXTURE WITH PLANT SAFENING AGENT | HOECHST SCHERING AGREVO GMBH (DE) | 1999-10-26 | — | — | US | claimed |
| US-5824377-A | POLYSILOXANE HAVING PENDANT CINNAMOYL GROUP | LG ELECTRONICS INC. (KR) | 1998-10-20 | — | — | US | claimed |
| US-5538823-A | Liquid crystal device utilizing thermostable polymeric material | GOLDSTAR CO., LTD. (KR) | 1996-07-23 | — | — | US | claimed |
| EP-0228172-B1 | PREPARATION OF 6-SUBSTITUTED 4-CHROMANONES | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0095932-B1 | THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1986-08-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | AKR1C3 3104/4885AKR1C1 2446/4885CYP2C9 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.