SCHEMBL7074202

SCHEMBL7074202

N#Cc1cc(C#N)cc(Oc2cccc(Oc3nccc(C(F)(F)F)n3)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 5/20 0.44
GPR119 Q8TDV5 1/20 0.38
P2RY1 P47900 1/20 0.37
ALOX5AP P20292 2/20 0.37
FEN1 P39748 2/20 0.37
LOX P28300 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
CKS1B P61024 1/20 0.37
SKP2 Q13309 1/20 0.37
EPAS1 Q99814 1/20 0.37
AR P10275 2/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
RAB9A P51151 1/20 0.36
IDH1 O75874 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074411 0.81 MEN1 (0.50) CKS1BSKP2RAB9AFFAR1FFAR4
SCHEMBL5217466 0.78 TGFBR1 (0.40) SYKALOX5APFEN1LOXLOXL2
SCHEMBL3665766 0.76 BLM (0.47) SYKALOX5APFEN1LOXLOXL2
SCHEMBL18004873 0.74 SYK (0.40) SYKGPR119ALOX5APFEN1AR
SCHEMBL7070749 0.74 SMN1; SMN2 (0.50) EPAS1ARRAB9ASLC6A2SLC6A4
SCHEMBL7077333 0.74 POLB (0.50) P2RY1EPAS1ARCYP2C9CYP2C19
SCHEMBL7072035 0.74 POLB (0.50) P2RY1EPAS1ARCYP2C9CYP2C19
SCHEMBL7129617 0.74 F10 (0.40)
SCHEMBL7071618 0.74 POLB (0.44) P2RY1EPAS1ARCYP2C9CYP2C19
SCHEMBL6579304 0.73 MAP4K4 (0.53) SYKCKS1BSKP2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 SYK 4082/4885GPR119 2636/4885P2RY1 2729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.