Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073594 | 0.90 | PKM (0.72) | PKMMEN1RAB9AKMT2AF10 | |
| SCHEMBL7074851 | 0.87 | GAA (0.63) | PKMKMT2AGAAALDH1A1LMNA | |
| SCHEMBL5735860 | 0.86 | F10 (0.80) | PKMMEN1RAB9AKMT2AF10 | |
| SCHEMBL7069339 | 0.85 | CNR1 (0.55) | PKMKMT2AF10GAAALDH1A1 | |
| SCHEMBL10064232 | 0.85 | PKM (0.74) | PKMMEN1RAB9AKMT2AGAA | |
| SCHEMBL7074115 | 0.84 | KDM4E (0.59) | PKMMEN1RAB9AKMT2AF10 | |
| SCHEMBL7070571 | 0.83 | GAA (0.58) | PKMRAB9AKMT2AF10GAA | |
| SCHEMBL7650417 | 0.82 | PKM (0.61) | PKMMEN1RAB9AKMT2AF10 | |
| SCHEMBL7071507 | 0.82 | MAPT (0.59) | PKMKMT2AF10GAAALDH1A1 | |
| SCHEMBL10081830 | 0.82 | CNR1 (0.72) | PKMMEN1RAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |