Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074438 | 0.85 | F10 (0.69) | L3MBTL1F10KMT2A | |
| SCHEMBL7074428 | 0.85 | PKM (0.62) | CNR1F10GAAPKMALDH1A1 | |
| SCHEMBL7070571 | 0.84 | GAA (0.58) | CNR1F10GAAPKMALDH1A1 | |
| SCHEMBL7071507 | 0.84 | MAPT (0.59) | CNR1L3MBTL1F10GAAPKM | |
| SCHEMBL7074851 | 0.84 | GAA (0.63) | CNR1GAAPKMALDH1A1F2 | |
| SCHEMBL7070008 | 0.83 | GAA (0.56) | CNR1F10GAAPKMALDH1A1 | |
| SCHEMBL7075152 | 0.82 | CNR1 (0.51) | CNR1F10GAAPKMALDH1A1 | |
| Acetic Acid SCHEMBL27568115 | 0.81 | F10 (0.64) | L3MBTL1F10KMT2A | |
| SCHEMBL7074639 | 0.81 | ALDH1A1 (0.55) | CNR1F10GAAPKMALDH1A1 | |
| SCHEMBL7074218 | 0.79 | ALDH1A1 (0.67) | CNR1GAAPKMALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |