Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361672 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRPOLBLMNA | |
| SCHEMBL6901115 | 0.80 | POLB (0.69) | ALDH1A1TDP1TSHRPOLBLMNA | |
| SCHEMBL5717558 | 0.79 | ALDH1A1 (0.73) | ALDH1A1TDP1TSHRPOLBLMNA | |
| SCHEMBL27363104 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRPOLBMEN1 | |
| SCHEMBL27362667 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRPOLBLMNA | |
| SCHEMBL13451413 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRLMNAHPGD | |
| Sumiki'S Acid SCHEMBL29706392 | 0.75 | TDP1 (1.00) | ALDH1A1TDP1TSHRPOLBL3MBTL1 | |
| Sumiki'S Acid SCHEMBL50822 | 0.75 | TDP1 (1.00) | ALDH1A1TDP1TSHRPOLBL3MBTL1 | |
| SCHEMBL13402907 | 0.75 | POLB (0.61) | ALDH1A1TDP1TSHRPOLBLMNA | |
| SCHEMBL28791562 | 0.74 | TDP1 (0.58) | ALDH1A1TDP1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118671244-A | Synchronous detection method for evaluating urine biomarkers exposed by various hot processing pollutants and application thereof | 浙江大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118671244-A | Synchronous detection method for evaluating urine biomarkers exposed by various hot processing pollutants and application thereof | 浙江大学 | 2024-09-20 | — | — | CN | disclosed |
| EP-0572560-B1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-1992014456-A1 | USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY | SHAPIRO HOWARD K (US) | 1992-09-03 | — | — | WO | disclosed |