Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361672 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL16473869 | 0.79 | MITF (0.55) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL13451413 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRLMNAHPGD | |
| SCHEMBL27363104 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL7074467 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL23011745 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL28791562 | 0.71 | TDP1 (0.58) | ALDH1A1TDP1TSHRLMNAMAPT | |
| SCHEMBL855399 | 0.71 | TDP1 (0.67) | ALDH1A1TDP1TSHRKMT2AHPGD | |
| SCHEMBL2031143 | 0.70 | HTT (0.76) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL18026626 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |